Biohybrid systems are systems formed by at least one biological component – i.e. already existing in living systems – and at least one artificial– newly engineered – component. Biological and artificial components are not independent, but are passing informationeither in one or both directions, thereby forming a new hybrid bio-artificial entity. Biohybrid systems usually involve structures from the nanoscale – i.e. molecular – to the macroscale – i.e. entire organs or body parts – level.